The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2021
Filed:
May. 23, 2017
Bayer Pharma Aktiengesellschaft, Berlin, DE;
Deutsches Krebsforschungszentrum (Dkfz), Heidelberg, DE;
Norbert Schmees, Berlin, DE;
Ilona Gutcher, Berlin, DE;
Horst Irlbacher, Berlin, DE;
Benjamin Bader, Berlin, DE;
Na Zhao, Beijng, CN;
Michael Platten, Heidelberg, DE;
Ulrike Röhn, Berlin, DE;
Ludwig Zorn, Berlin, DE;
Lars Röse, Berlin, DE;
Detlef Stöckigt, Potsdam, DE;
BAYER PHARMA AKTIENGESELLSCHAFT, Berlin, DE;
DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ), Heidelberg, DE;
Abstract
The present invention covers 3-oxo-2,6-diphenyl-2,3-dihydropyridazine-4-carboxamide compounds of general formula (I): in which R1, R2, R3, R4, R5 and R6 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of cancer or conditions with 10 dysregulated immune responses or other disorders associated with aberrant AHR signaling, as a sole agent or in combination with other active ingredients.