The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 15, 2021

Filed:

Jun. 05, 2018
Applicant:

Orano Med, Courbevoie, FR;

Inventors:

Julien Torgue, Gaithersburg, MD (US);

Patrick Maquaire, Tourlaville, FR;

John Young, Woodridge, IL (US);

Gilbert Andreoletti, Equeurdreville, FR;

Patrick Bourdet, Kensington, MD (US);

Assignee:

ORANO MED, Châtillon, FR;

Attorney:
Int. Cl.
CPC ...
G21G 1/00 (2006.01); G01N 30/84 (2006.01); G01D 15/12 (2006.01); G01N 30/06 (2006.01); B01D 15/42 (2006.01); A61K 51/12 (2006.01); C22B 13/02 (2006.01); C22B 13/06 (2006.01); C22C 11/00 (2006.01); B01D 15/12 (2006.01); G21G 4/08 (2006.01);
U.S. Cl.
CPC ...
G21G 1/0005 (2013.01); A61K 51/12 (2013.01); B01D 15/12 (2013.01); B01D 15/424 (2013.01); C22B 13/02 (2013.01); C22B 13/06 (2013.01); C22C 11/00 (2013.01); G01N 30/06 (2013.01); G01N 30/84 (2013.01); G01N 2030/067 (2013.01); G21G 4/08 (2013.01); G21G 2001/0094 (2013.01);
Abstract

The invention relates to a method for preparing lead (212) for medical use. This method comprises the production of lead (212) by the decay of radium (224) in a generator comprising a solid medium to which the radium (224) is bound, followed by the extraction of the lead (212) from the generator in the form of an aqueous solution A1, characterised in that the lead (212) contained in the aqueous solution A1 is purified from the radiological and chemical impurities, also contained in said aqueous solution, by a liquid chromatography on a column. The invention also relates to an apparatus specially designed for automated implementation in a closed system of said method. It further relates to lead (212) produced by means of this method and this apparatus. Applications: manufacture of radiopharmaceuticals based on lead (212), useful in nuclear medicine for the treatment of cancers, particularly by a-radioimmunotherapy, or for medical imaging, in both humans and animals.


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