The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 15, 2021

Filed:

Dec. 17, 2019
Applicant:

Biospex, Inc., San Jose, CA (US);

Inventors:

Wei Yang, Los Altos, CA (US);

Shu Zhang, Fremont, CA (US);

Changqing Wang, Livermore, CA (US);

Ming Chai, Union City, CA (US);

Assignee:

BioSpex, Inc., San Jose, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/65 (2006.01); G01J 3/44 (2006.01); G01N 33/66 (2006.01); G01N 33/92 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 21/658 (2013.01); G01J 3/44 (2013.01); G01N 33/574 (2013.01); G01N 33/66 (2013.01); G01N 33/92 (2013.01); G01N 2021/655 (2013.01);
Abstract

Systems and methods for hybrid time-resolved and time-shifted spectroscopy for measuring biological analytes are disclosed. Exemplary methods include: illuminating an analyte using first light from and excitation source, the first light having a first excitation wavelength; detecting a first spectrum from the analyte illuminated by the first light using a time-resolved spectroscopy technique, the first spectrum including a first Raman signal and fluorescence; illuminating the analyte using second light, the second light having a second excitation wavelength; detecting a second spectrum using a time-resolved spectroscopy technique; illuminating the analyte using third light, the third light having a third excitation wavelength; detecting a third spectrum; recovering the first Raman signal using the first spectrum, the second spectrum, and the third spectrum using an inverse transform; and using the first Raman signal to identify and measure at least one molecule of the analyte using a database of identified Raman signals.


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