The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Mar. 31, 2017
Applicant:
Lallemand Inc., Rexdale, CA;
Inventors:
Caroline Wilde, Montreal, CA;
Corinne Cluis, Montreal, CA;
Assignee:
Lallemand Inc., Rexdale, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01); C07K 14/39 (2006.01); C12N 9/88 (2006.01); C12N 15/52 (2006.01); C12N 15/81 (2006.01); C12P 1/02 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C07K 14/39 (2013.01); C12N 9/88 (2013.01); C12N 15/52 (2013.01); C12N 15/81 (2013.01); C12P 1/02 (2013.01); C12Y 401/02005 (2013.01);
Abstract
The disclosure concerns a genetically modified host cell for the production and accumulation of glutathione (GSH). The genetically modified host cell can allow the expression of a mutated Cys4p whose activity is increased. In addition or alternatively, the genetically modified host cell can express a mutated Yap1p whose translocation from the nucleus to the cytoplasm is reduced. Furthermore, in addition or alternatively, the genetically modified host cell can express an heterologous threonine aldolase (Gly1p).