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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11034990 B1

PDFFull Text
Date of Patent:
Jun. 15, 2021

Filed:

Mar. 31, 2017

Optimized host cells for the production of glutathione

Applicant:

Lallemand Inc., Rexdale, CA;

Inventors:

Caroline Wilde, Montreal, CA;

Corinne Cluis, Montreal, CA;

Assignee:

Lallemand Inc., Rexdale, CA;

Attorney:

Seed IP Law Group LLP

Primary Examiner:

Anand U Desai

Int. Cl.
CPC ...
C12P 21/02 (2006.01); C07K 14/39 (2006.01); C12N 9/88 (2006.01); C12N 15/52 (2006.01); C12N 15/81 (2006.01); C12P 1/02 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C07K 14/39 (2013.01); C12N 9/88 (2013.01); C12N 15/52 (2013.01); C12N 15/81 (2013.01); C12P 1/02 (2013.01); C12Y 401/02005 (2013.01);
Abstract

The disclosure concerns a genetically modified host cell for the production and accumulation of glutathione (GSH). The genetically modified host cell can allow the expression of a mutated Cys4p whose activity is increased. In addition or alternatively, the genetically modified host cell can express a mutated Yap1p whose translocation from the nucleus to the cytoplasm is reduced. Furthermore, in addition or alternatively, the genetically modified host cell can express an heterologous threonine aldolase (Gly1p).

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Wilde, Caroline. (2021). Optimized host cells for the production of glutathione (U.S. Patent No. 11034990). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11034990

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