The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Feb. 26, 2018
Applicant:
Institute for Cancer Research, Philadelphia, PA (US);
Inventors:
Amriti R. Lulla, Philadelphia, PA (US);
Wafik S. El-Deiry, Philadelphia, PA (US);
Assignee:
Institute For Cancer Research, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61P 35/00 (2018.01); C12N 15/113 (2013.01); A61K 45/06 (2013.01); C12N 2310/141 (2013.01); C12N 2320/30 (2013.01);
Abstract
The present disclosure provides miRNA mimics targeting CDK4 and/or CDK6, and compositions comprising the same. Methods for the treatment of tumors, including but not limited to colon cancer, comprising administering a modified oligonucleotide comprising a miRNA are also disclosed herein.