The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Jul. 09, 2020
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Stuart Milstein, Cambridge, MA (US);
Kirk Brown, Cambridge, MA (US);
Jayaprakash Nair, Cambridge, MA (US);
Martin Maier, Cambridge, MA (US);
Vasant Jadhav, Cambridge, MA (US);
Mark Keating, Cambridge, MA (US);
Adam Castoreno, Cambridge, MA (US);
Patrick Haslett, Cambridge, MA (US);
Mangala Meenakshi Soundarapandian, Cambridge, MA (US);
Kevin Fitzgerald, Cambridge, MA (US);
ALNYLAM PHARMACEUTICALS, INC., Cambridge, MA (US);
Abstract
The disclosure relates to double stranded ribonucleic acid (dsRNAi) agents and compositions targeting the APP gene, as well as methods of inhibiting expression of an APP gene and methods of treating subjects having an APP-associated disease or disorder, such as cerebral amyloid angiopathy (CAA) and early onset familial Alzheimer disease (EOFAD or eFAD), using such dsRNAi agents and compositions.