The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Nov. 13, 2019
Pieris Pharmaceuticals Gmbh, Freising-Weihenstephan, DE;
Rachida Siham Bel Aiba, Munich, DE;
Andrea Allersdorfer, Wolnzach, DE;
Alexander Wiedenmann, Ulm, DE;
Christine Rothe, Dachau, DE;
Shane Olwill, Freising, DE;
Hendrik Gille, Munich, DE;
Laurent Audoly, Mahwah, NJ (US);
Pieris Pharmaceuticals GmbH, Hallbergmoos, DE;
Abstract
The present disclosure provides hNGAL muteins that bind Ang-2 and can be used in various application including pharmaceutical applications, for example, to inhibit or reduce angiogenesis. The present disclosure also concerns methods of making one or more muteins described herein as well as compositions and combinations comprising one or more of such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and to methods for generation of such muteins and nucleic acid molecules. In addition, the application discloses therapeutic and/or diagnostic uses of these muteins as well as compositions and combinations comprising one or more of such muteins.