The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Dec. 06, 2017
Applicant:
Valorbec, Société En Commandite, Montréal, CA;
Inventors:
Pasquale Forgione, Montréal, CA;
Alisa Julienne Piekny, Lachine, CA;
Dilan Boodhai Jaunky, Montréal, CA;
Fei Chen, Pierrefonds, CA;
Jiang Tian Liu, Montréal, CA;
Assignee:
VALORBEC, SOCIÉTÉ EN COMMANDITE, Montréal, CA;
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01); C07D 495/14 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61P 35/00 (2018.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 495/14 (2013.01);
Abstract
The present disclosure relates to fused N-arylsulfonamidyl-thienoisoquinoline compounds, derivatives and pharmaceutical compositions thereof, and methods and uses in inhibiting cancer cell growth, along with a supplemental anti-cancer agent. Centrosome targeting and microtubule depolymerisation are attractive in designing the present chemotherapeutic compounds. The various diseases and conditions treated include various types of cell cancers, and in vitro inhibition.