The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Nov. 14, 2018
Applicants:
University of Kansas, Lawrence, KS (US);
Victoria Link Limited, Wellington, NZ;
Inventors:
Thomas E. Prisinzano, Lawrence, KS (US);
Rachel Saylor Crowley, San Diego, CA (US);
Bronwyn Maree Daken Kivell, Wellington, NZ;
Assignees:
UNIVERSITY OF KANSAS, Lawrence, KS (US);
VICTORIA LINK LIMITED, Wellington, NZ;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/14 (2006.01); C07D 407/12 (2006.01); C07D 407/14 (2006.01); A61P 25/00 (2006.01); A61P 25/04 (2006.01); A61P 29/00 (2006.01); C07D 407/04 (2006.01);
U.S. Cl.
CPC ...
C07D 407/14 (2013.01); A61P 29/00 (2018.01); C07D 405/14 (2013.01); C07D 407/04 (2013.01);
Abstract
The present technology is directed to compounds, compositions, and methods related to non-morphinan-like mu opioid receptor agonists of Formula I. Compounds of the present technology demonstrate remarkable potency and selectivity for the mu opioid receptor, while also exhibiting a significant reduction (or, essentially, absence) of the negative side effects of many morphine-derived compounds.