The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Nov. 20, 2015
University of Maryland, Baltimore, Baltimore, MD (US);
The Johns Hopkins University, Baltimore, MD (US);
Graeme F. Woodworth, Baltimore, MD (US);
Jeffrey A. Winkles, Frederick, MD (US);
Anthony J. Kim, Clarksville, MD (US);
Craig S. Schneider, Severna Park, MD (US);
Justin Hanes, Baltimore, MD (US);
University Of Maryland, Baltimore, Baltimore, MD (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
Provided are targeted structure-specific particulate-based delivery systems comprising: a nanoparticle; a PEG polymer coating on the surface of the nanoparticle; a targeting moiety conjugated on a surface of the nanoparticle and configured to promote specific binding to a cell surface molecule expressed by a target cell; and a biologically active agent in or on the nanoparticle, wherein the biologically active agent is selected to enhance a desired response in a target cell intracellularly or extracellularly. Methods of treating a disease or disorder administering the delivery system are contemplated.