The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Jul. 06, 2020
Applicant:
Sichuan Agricultural University, Sichuan, CN;
Inventors:
Anchun Cheng, Sichuan, CN;
Xingjian Wen, Sichuan, CN;
Mingshu Wang, Sichuan, CN;
Liping Wu, Sichuan, CN;
Assignee:
SICHUAN AGRICULTURAL UNIVERSITY, Chengdu, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 39/29 (2006.01); A61P 31/14 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/29 (2013.01); A61P 31/14 (2018.01); C12N 7/00 (2013.01); A61K 2039/525 (2013.01); A61K 2039/552 (2013.01); C12N 2770/32421 (2013.01); C12N 2770/32434 (2013.01); C12N 2770/32452 (2013.01);
Abstract
Disclosed herein are a duck hepatitis A virus type 3 (DHAV-3) mutant CH-P60-117C and a construction method thereof. The DHAV-3 mutant CH-P60-117C is constructed by mutating A at position 117 of 5'-UTR of the genome of the DHAV-3 virulent strain to C; mutating T at position 1142 to A to mutate tyrosine-164 of VP0 protein of the parent strain to asparagine; and mutating C at position 4334 to A so that leucine-71 of the viral protein 2C of the parent strain is mutated to isoleucine.