The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Mar. 09, 2020
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Catherine Jorand-LeBrun, Arlington, MA (US);
Roch Boivin, North Chelmsford, MA (US);
Igor Mochalkin, Westford, MA (US);
Theresa Johnson, Salem, MA (US);
Nina Linde, Frankfurt am Main, DE;
Doreen Musch, Reinheim, DE;
Deepak Kumar, Canton, MA (US);
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/497 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07D 401/04 (2006.01); C07D 491/107 (2006.01); C07D 513/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/497 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07D 401/04 (2013.01); C07D 491/107 (2013.01); C07D 513/10 (2013.01);
Abstract
The invention relates to carboxamide-pyrimidine derivatives of the general formula I, or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.