The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 15, 2021

Filed:

Apr. 18, 2019
Applicant:

University of Florida Research Foundation, Inc., Gainesville, FL (US);

Inventors:

Anuj Chauhan, Golden, CO (US);

Phillip J. Dixon, Gainesville, FL (US);

Poorvajan Sekar, Gainesville, FL (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61J 1/14 (2006.01); B01J 20/26 (2006.01); B01J 20/28 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 31/498 (2006.01); A61K 31/5377 (2006.01); A61K 47/18 (2017.01); B01D 15/00 (2006.01);
U.S. Cl.
CPC ...
A61J 1/1468 (2015.05); A61J 1/1443 (2013.01); A61J 1/1475 (2013.01); B01J 20/261 (2013.01); B01J 20/267 (2013.01); B01J 20/28016 (2013.01); B01J 20/28042 (2013.01); A61J 1/1456 (2015.05); A61K 9/0048 (2013.01); A61K 9/08 (2013.01); A61K 31/498 (2013.01); A61K 31/5377 (2013.01); A61K 47/186 (2013.01); B01D 15/00 (2013.01);
Abstract

A particulate plug for removing a preservative from a solution, suspension, or emulsion comprising a drug is presented. The plug comprises microparticles of a homopolymer comprising a hydrophilic repeating unit or of a copolymer comprising at least one hydrophilic repeating unit and at least one hydrophobic repeating unit. The microparticles are irregular-shaped rigid aggregates and are sized and packed to yield a hydraulic permeability greater than 0.01 Da. The homopolymers have absorbed portions of a preservative to be removed and/or a drug for delivery in solution, as can the copolymer.


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