The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Jun. 08, 2015
Applicant:
Trustees of Boston University, Boston, MA (US);
Inventors:
Wilson W. Wong, Brookine, MA (US);
Benjamin Harris Weinberg, Boston, MA (US);
Assignee:
TRUSTEES OF BOSTON UNIVERSITY, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
G06N 3/12 (2006.01); C12N 15/10 (2006.01); C12N 5/0783 (2010.01); C12N 5/0781 (2010.01); G16B 5/00 (2019.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
G06N 3/123 (2013.01); C12N 5/0635 (2013.01); C12N 5/0636 (2013.01); C12N 15/1082 (2013.01); C12N 15/11 (2013.01); C12N 15/113 (2013.01); G16B 5/00 (2019.02); C12N 2840/002 (2013.01);
Abstract
The invention provides, inter alia, recombinase-based systems that provide for integrated logic and memory in living cells such as mammalian cells. The nucleic acid cassettes, switches, and systems described herein allow for control of gene expression or gene regulation. The invention also provides nucleic acid-based switches for adopted T-cell therapy.