The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 08, 2021

Filed:

Oct. 26, 2018
Applicant:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Inventors:

Sang Jin Lee, Clemmons, NC (US);

James J. Yoo, Winston-Salem, NC (US);

Young Min Ju, Winston-Salem, NC (US);

Anthony Atala, Winston-Salem, NC (US);

Assignee:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
D01D 5/00 (2006.01); A61L 27/24 (2006.01); A61K 35/44 (2015.01); C07K 16/46 (2006.01); A61K 31/737 (2006.01); A61K 38/36 (2006.01); A61K 38/18 (2006.01); A61K 31/729 (2006.01); A61K 38/39 (2006.01); C07K 16/28 (2006.01); C07D 315/00 (2006.01); A61K 31/728 (2006.01); D01F 6/92 (2006.01); C07K 16/18 (2006.01); D01F 1/10 (2006.01); D01F 6/62 (2006.01); D01F 4/00 (2006.01);
U.S. Cl.
CPC ...
D01D 5/003 (2013.01); A61K 31/728 (2013.01); A61K 31/729 (2013.01); A61K 31/737 (2013.01); A61K 35/44 (2013.01); A61K 38/1858 (2013.01); A61K 38/363 (2013.01); A61K 38/39 (2013.01); A61L 27/24 (2013.01); C07D 315/00 (2013.01); C07K 16/18 (2013.01); C07K 16/289 (2013.01); C07K 16/46 (2013.01); D01D 5/0076 (2013.01); D01F 1/10 (2013.01); D01F 6/92 (2013.01); C07K 16/2896 (2013.01); D01F 4/00 (2013.01); D01F 6/625 (2013.01);
Abstract

The invention is directed to products and methods for preparing self-seeding vascular constructs generated as a bi-layered electrospun matrices, conjugated with EPC-specific antibodies and anti-thrombogenic agents on the inner surfaces of their lumens.


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