The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Jan. 06, 2020
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventors:
Wanqing Liu, Zionsville, IN (US);
Yoon Yeo, West Lafayette, IN (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01); A61K 31/7088 (2006.01); A61K 47/59 (2017.01); A61K 47/58 (2017.01); A61K 47/54 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 47/554 (2017.08); A61K 47/58 (2017.08); A61K 47/59 (2017.08); A61K 47/6923 (2017.08); A61K 47/6933 (2017.08); C12N 2310/14 (2013.01); C12N 2310/351 (2013.01); C12N 2320/32 (2013.01); C12N 2320/34 (2013.01); C12Y 301/01003 (2013.01);
Abstract
The invention provides siRNA compositions that specifically downregulates expression of a variant of the PNPLA3 gene and methods of use thereof for treating a chronic liver disease or alcoholic liver disease (ALD).