The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Jul. 06, 2018
Osaka University, Suita, JP;
Knc Laboratories Co., Ltd., Kobe, JP;
Aichi Medical University, Nagakute, JP;
Yoshitaka Nagai, Suita, JP;
Kazuhiro Maeta, Suita, JP;
Toshihide Takeuchi, Suita, JP;
Masahiro Neya, Kobe, JP;
Tsuyoshi Fujihara, Kobe, JP;
Seiji Matsuda, Kobe, JP;
Gen Sobue, Nagoya, JP;
Shinsuke Ishigaki, Nagoya, JP;
Kentaro Sahashi, Nagoya, JP;
Osaka University, Suita, JP;
KNC Laboratories Co., Ltd., Kobe, JP;
Aichi Medical University, Nagakute, JP;
Abstract
The present invention provides a suppression type antisense oligonucleotide targeting TDP-43 mRNA, containing a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a nucleotide sequence shown in any of SEQ ID NOs: 2-4, and a promotion type antisense oligonucleotide targeting TDP-43 mRNA, containing a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a nucleotide sequence shown in SEQ ID NO: 5.