The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Jun. 08, 2017
Applicant:
Changzhou Bojia Biotechnology Co., Ltd, Jiangsu, CN;
Inventor:
Shaoxiong Wang, Shanghai, CN;
Assignee:
CHANGZHOU BOJIA BIOTECHNOLOGY CO., LTD, Jiangsu, CN;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/18 (2006.01); C07K 16/40 (2006.01); A61P 3/06 (2006.01); C12N 9/64 (2006.01); C12N 15/62 (2006.01); G01N 33/58 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 39/395 (2013.01); A61P 3/06 (2018.01); C12N 9/6424 (2013.01); C12N 15/62 (2013.01); C12Y 304/21061 (2013.01); G01N 33/582 (2013.01); G01N 33/583 (2013.01); A61K 38/00 (2013.01); C07K 2317/32 (2013.01); C07K 2317/565 (2013.01); C07K 2319/30 (2013.01);
Abstract
Provided is a long-acting PCSK9-specific binding protein and application thereof. Provided is an MV072 protein with unique complementarity-determining regions, i.e., a binding protein specifically binding to proprotein convertase subtilisin kexin type 9 (PCSK9). The protein can specifically bind to PCSK9, effectively inhibit the function of PCSK9 and reduce plasma LDL cholesterol level. Further provided is an application of the binding protein in treating diseases related to or influenced by the function of PCSK9.