The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 08, 2021

Filed:

May. 31, 2018
Applicant:

Nexel Co., Ltd., Seoul, KR;

Inventors:

Choong Seong Han, Seoul, KR;

Dong Hun Woo, Seoul, KR;

Gun Sik Cho, Daejeon, KR;

Jeong Seong Kim, Hanam-si, KR;

Geun Ho An, Seoul, KR;

Hye Ryeon Jeon, Seongnam-si, KR;

Assignee:

NEXEL CO., LTD., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 14/47 (2006.01); C07K 14/485 (2006.01); A61P 1/16 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/485 (2013.01); A61K 38/1709 (2013.01); A61P 1/16 (2018.01); C07K 14/47 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention relates to a recombinant protein for preventing or treating tissue fibrosis, which is based on milk fat globule-EGF factor 8 (MFG-E8) protein and comprises the amino acid sequence of SEQ ID NO: 1, and to a composition for preventing or treating tissue fibrosis, which comprises the recombinant protein. The level of the effect of preventing or treating tissue fibrosis by the recombinant protein of the present invention is significantly improved compared to that of conventional milk fat globule-EGF factor 8 (MFG-E8) protein, so that the level of tissue fibrosis can be restored to a level very close to that in normal tissue by the prevention and treatment of tissue fibrosis.


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