The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Mar. 19, 2018
Univerzita Palackeho V Olomouci, Olomouc, CZ;
Tomas Gucky, Mladejovice, CZ;
Eva Reznickova, Olomouc, CZ;
Radek Jorda, Olomouc, CZ;
Vladimir Krystof, Olomouc, CZ;
Miroslav Strnad, Olomouc, CZ;
Tereza Radosova Muchova, Vyskov, CZ;
Vladimir Divoky, Olomouc, CZ;
UNIVERZITA PALACKEHO V OLOMOUCI, Olomouc, CZ;
Abstract
The present invention relates to novel 2,6-disubstituted-9-cyclopentyl-9H-purines of general formula I, capable of inhibiting the activity of kinases such as FLT3, CDKs and PDGFRs in cancer and other related proliferative diseases. The invention further includes pharmaceutical compositions containing the 2,6-disubstituted-9-cyclopentyl-9H-purines. Compounds of the present invention can be used as active ingredients of a pharmaceutical compositions for treating acute myeloid leukemia (AML).