The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Aug. 12, 2016
Applicant:
Novartis Pharmaceuticals Corporation, East Hanover, NJ (US);
Inventors:
Assignee:
NOVARTIS PHARMACEUTICALS CORPORATION, East Hanover, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/06 (2006.01); A61K 31/4709 (2006.01); C07D 217/26 (2006.01); A61K 31/4725 (2006.01); A61K 45/06 (2006.01); C07D 405/10 (2006.01); A61K 9/06 (2006.01); A61K 9/08 (2006.01); A61K 47/02 (2006.01); A61K 47/06 (2006.01); A61K 47/10 (2017.01); A61K 47/14 (2017.01); A61K 47/22 (2006.01); A61K 47/38 (2006.01); C07C 317/48 (2006.01); C07D 217/02 (2006.01); C07D 217/04 (2006.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
C07D 405/06 (2013.01); A61K 9/06 (2013.01); A61K 9/08 (2013.01); A61K 31/4709 (2013.01); A61K 31/4725 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); A61K 47/06 (2013.01); A61K 47/10 (2013.01); A61K 47/14 (2013.01); A61K 47/22 (2013.01); A61K 47/38 (2013.01); C07C 317/48 (2013.01); C07D 217/02 (2013.01); C07D 217/04 (2013.01); C07D 217/26 (2013.01); C07D 405/10 (2013.01); A61K 47/183 (2013.01);
Abstract
Novel crystalline polymorphic forms, Forms A, B, C, D, and E of a compound of Formula I, which has been found to be a potent inhibitor of LFA-1, are disclosed. Methods of preparation and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed in this invention.