The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 08, 2021

Filed:

Feb. 22, 2019
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Daniel Sutherlin, South San Francisco, CA (US);

Steven McKerrall, South San Francisco, CA (US);

Kwong Wah Lai, Shanghai, CN;

Zhiguo Liu, Shanghai, CN;

Wenfeng Liu, Shanghai, CN;

Ramsay Beveridge, Montreal, CA;

Jean-Philippe Leclerc, Montreal, CA;

Alexandre Lemire, Montreal, CA;

Liang Zhao, Montreal, CA;

Claudio Sturino, Montreal, CA;

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/12 (2006.01); C07D 403/12 (2006.01); C07D 233/96 (2006.01); C07D 401/12 (2006.01); A61P 17/04 (2006.01); C07D 263/52 (2006.01); C07D 305/06 (2006.01); C07D 401/14 (2006.01); A61K 31/506 (2006.01); A61K 31/538 (2006.01); C07B 59/00 (2006.01); A61K 31/63 (2006.01); A61K 45/06 (2006.01); C07D 239/69 (2006.01); A61K 31/505 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/538 (2013.01); A61K 31/63 (2013.01); A61K 45/06 (2013.01); A61P 17/04 (2018.01); C07B 59/002 (2013.01); C07D 233/96 (2013.01); C07D 239/69 (2013.01); C07D 263/52 (2013.01); C07D 305/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 413/12 (2013.01);
Abstract

The invention provides benzene sulfonamides and pharmaceutically acceptable salt thereof that are useful as sodium channel blockers for the treatment of, for example, pain. The following compound is illustrative:


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