The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
May. 19, 2017
Applicant:
Polytherics Limited, Cambridge, GB;
Inventor:
Antony Godwin, London, GB;
Assignee:
POLYTHERICS LIMITED, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 47/68 (2017.01); A61K 31/404 (2006.01); A61K 31/5365 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6951 (2017.08); A61K 31/404 (2013.01); A61K 31/5365 (2013.01); A61K 47/6817 (2017.08); A61K 47/6849 (2017.08); A61K 47/6889 (2017.08);
Abstract
A conjugate of a protein or peptide conjugated to a therapeutic, diagnostic or labelling agent via a linker, in which the linker includes a protein or peptide bonding portion having the general formula: in which Pr represents said protein or peptide, each Nu represents a nucleophile present in or attached to the protein or peptide, each of A and B independently represents a Calkylene or alkenylene chain, and W' represents an electron withdrawing group or a group obtained by reduction of an electron withdrawing group; and in which the linker also includes a cyclodextrin. The invention also provides reagents for making such conjugates.