The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Oct. 23, 2017
Applicant:
Universita' Degli Studi Di Trento, Trento, IT;
Inventors:
Assignee:
BIOMVIS SRL, Siena, IT;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); C12N 1/00 (2006.01); C12N 1/20 (2006.01); A61K 39/09 (2006.01); A61K 39/085 (2006.01); C07K 14/31 (2006.01); C07K 14/315 (2006.01); C07K 14/195 (2006.01); A61K 39/00 (2006.01); C12R 1/19 (2006.01); C12N 15/70 (2006.01);
U.S. Cl.
CPC ...
A61K 39/092 (2013.01); A61K 39/02 (2013.01); A61K 39/085 (2013.01); C07K 14/195 (2013.01); C07K 14/31 (2013.01); C07K 14/315 (2013.01); A61K 2039/60 (2013.01); A61K 2039/6018 (2013.01); C12N 1/20 (2013.01); C12N 15/70 (2013.01); C12R 1/19 (2013.01);
Abstract
This invention relates to outer membrane vesicles (OMVs) from Gram-negative bacteria. The vesicles comprise heterologous proteins or immunogenic fragments thereof expressed as lipoproteins in their membrane. The OMVs of the invention are capable of eliciting an immune response to the heterologous protein or to a fragment thereof when administered to a mammal. Other aspects of the invention relate to methods of preparing the OMVs and immunogenic compositions containing the same.