The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Jan. 10, 2020
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Darrell J. Irvine, Arlington, MA (US);
Ron Weiss, Newton, MA (US);
Tasuku Kitada, Cambridge, MA (US);
Mariane Melo, Stoneham, MA (US);
Yuan Zhang, Cambridge, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 38/20 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5123 (2013.01); A61K 9/0019 (2013.01); A61K 38/2086 (2013.01); A61P 35/00 (2018.01);
Abstract
Disclosed herein are lipid nanoparticles comprising 1,2-dioleoyl-3-trimethylammonium propane (DOTAP), 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), cholesterol, and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000](DSPE-PEG2000), compositions including such lipid nanoparticles, and methods of treatment using such lipid nanoparticles and compositions.