The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 2021

Filed:

Oct. 09, 2018
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Laura Waller, Berkeley, CA (US);

Zachary Phillips, Berkeley, CA (US);

Michael Chen, Irvine, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G02B 5/20 (2006.01); G02B 21/14 (2006.01); G02B 21/36 (2006.01); H04N 5/232 (2006.01); H04N 9/07 (2006.01);
U.S. Cl.
CPC ...
G02B 5/201 (2013.01); G02B 21/14 (2013.01); G02B 21/365 (2013.01); H04N 5/23229 (2013.01); H04N 5/23264 (2013.01); H04N 9/07 (2013.01); H04N 2209/043 (2013.01); H04N 2209/044 (2013.01);
Abstract

Systems and methods are disclosed for recovering both phase and amplitude of an arbitrary sample in an optical microscope from a single image, using patterned partially coherent illumination. This is realized through the use of a encoded light source which embeds several different illumination patterns into color channels. The sample is modulated by each illumination wavelength separately and independently of each other, but all of the channels are sensed by the imaging device in a single step. This color image contains information about the phase and amplitude of a sample encoded in each channel, and can be used to recover both amplitude and phase from this single image, at the incoherent resolution limit. Further, extensions of this method are shown which allow the same recovery of a sample whilst it is moving during a single exposure using a motion deblurring algorithm.


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