The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 2021
Filed:
Aug. 29, 2019
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventors:
Marxa L. Figueiredo, Lafayette, IN (US);
Charles Samuel Umbaugh, Heidelberg, DE;
Herman O. Sintim, West Lafayette, IN (US);
Adriana Diaz-Quinones, West Lafayette, IN (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/574 (2006.01); G16B 15/30 (2019.01); G16C 20/60 (2019.01); G16C 20/50 (2019.01); A61K 31/497 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); A61K 31/497 (2013.01); G01N 33/57434 (2013.01); G16B 15/30 (2019.02); G16C 20/50 (2019.02); G16C 20/60 (2019.02);
Abstract
An in silico screening method generated compounds that are against laminin receptor 37LR and their anti-cancer functions in prostate cancer cell lines are disclosed herein. A group of derivatives based on the hit compound from the in silico screening are synthesized and tested with improved ICvalue that can have relevant clinical use for prostate cancer or osteoarthritis.