The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 2021

Filed:

Aug. 29, 2018
Applicants:

The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Ashley Lynne Beckwith, Cambridge, MA (US);

Jeffrey Borenstein, Newton, MA (US);

Nathan Moore, Canton, MA (US);

Daniel Doty, Arlington, MA (US);

Luis Velasquez-Garcia, Cambridge, MA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12M 1/32 (2006.01); B01L 3/00 (2006.01); C12M 3/06 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5008 (2013.01); B01L 3/502761 (2013.01); C12M 23/12 (2013.01); G01N 33/5082 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/0684 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0877 (2013.01); B01L 2300/0883 (2013.01); B01L 2400/0463 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/086 (2013.01); C12M 23/16 (2013.01);
Abstract

This disclosure describes microfluidic tissue biopsy and immune response drug evaluation devices and systems. A microfluidic device can include an inlet channel having a first end configured to receive a fluid sample optionally containing a tissue sample. The microfluidic device can also include a tissue trapping region at the second end of the inlet channel downstream from the first end. The tissue trapping region can include one or more tissue traps configured to catch a tissue sample flowing through the inlet channel such that the fluid sample contacts the tissue trap. The microfluidic device can also include one or more channels providing an outlet.


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