The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 2021
Filed:
Oct. 03, 2017
Abbott Laboratories, Abbott Park, IL (US);
Jeffrey B. Huff, Lincolnshire, IL (US);
Mark A. Hayden, Ingleside, IL (US);
Peter J. Karabatsos, Glencoe, IL (US);
Andrew S. Schapals, Pleasant Prairie, WI (US);
Anthony S. Muerhoff, Kenosha, WI (US);
M. Felicia Bogdan, Gurnee, IL (US);
Thomas Leary, Kenosha, WI (US);
Shelley R. Holets-McCormack, Waukegan, IL (US);
Sophie Laurenson, Basel-Land, CH;
Andrew T. Fischer, Euless, TX (US);
Richard Haack, Skokie, IL (US);
Stefan Hershberger, Highland Park, IL (US);
Dustin House, Carrollton, TX (US);
Lei Qiao, Lake Bluff, IL (US);
M. Shawn Murphy, Allen, TX (US);
Mark R. Pope, Grayslake, IL (US);
Edna M. Prieto-Ballengee, Dallas, TX (US);
QiaoQiao Ruan, Kildeer, IL (US);
Pathik Soni, Chicago, IL (US);
Sergey Tetin, Lindenhurst, IL (US);
Lyle Yarnell, Richardson, TX (US);
ABBOTT LABORATORIES, Abbott Park, IL (US);
Abstract
Methods, devices, and systems for analyte analysis using a nanopore are disclosed. The methods, devices, and systems utilize a first and a second binding member that each specifically bind to an analyte in a biological sample. The method further includes detecting and/or counting a cleavable tag attached to the second binding member and correlating the presence and/or the number of tags to presence and/or concentration of the analyte. Certain aspects of the methods do not involve a tag, rather the second binding member may be directly detected/quantitated. The detecting and/or counting may be performed by translocating the tag/second binding member through a nanopore. Devices and systems that are programmed to carry out the disclosed methods are also provided.