The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 2021
Filed:
Dec. 18, 2018
Applicant:
Janssen Sciences Ireland Unlimited Company, County Cork, IE;
Inventors:
Daniel Boden, San Mateo, CA (US);
Helen Horton, Mol, BE;
Jean-Marc Edmond Fernand Marie Neefs, Lier, BE;
Soumitra Roy, Townsend, DE (US);
Dorien De Pooter, Veerle, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); A61P 31/20 (2006.01); C07K 14/005 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/12 (2013.01); A61K 39/12 (2013.01); A61P 31/20 (2018.01); C07K 14/005 (2013.01); A61K 39/00 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/53 (2013.01); C12N 2710/10343 (2013.01); C12N 2730/10122 (2013.01); C12N 2730/10134 (2013.01);
Abstract
Polynucleotides encoding hepatitis B virus (HBV) core antigen and polymerase antigen, and related combinations are described. Also described are vectors, such as DNA plasmids or viral vectors, expressing the HBV core and polymerase antigens, and immunogenic compositions containing the expression vectors. Methods of inducing an immune response against HBV or treating a HBV-induced disease, particularly in individuals having chronic HBV infection, using the immunogenic compositions are also described.