The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 2021
Filed:
Jun. 10, 2015
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Howard H. Chou, Berkeley, CA (US);
Jay D. Keasling, Berkeley, CA (US);
Sergey Zotchev, Trondheim, NO;
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); C07K 2319/00 (2013.01); C07K 2319/70 (2013.01); C07K 2319/80 (2013.01);
Abstract
The present invention provides for a synthetic transcription factor (TF) comprising a first peptide capable of binding a target ligand, a second peptide capable of binding a target DNA, and a peptide linker linking the first and second peptides. The present invention also provide for a system for modulating the mutagenesis frequency of a host cell. The host cell has a mutator rate (R) which is inversely proportional to a phenotypic trait (P).