The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 2021
Filed:
Jul. 17, 2019
Applicants:
Loyola University of Chicago, Chicago, IL (US);
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Daniel Paul Becker, Glenview, IL (US);
Tahirah K. Heath, Chicago, IL (US);
Cory Reidl, Franklin Grove, IL (US);
Walter Fast, Austin, TX (US);
Assignees:
LOYOLA UNIVERSITY OF CHICAGO, Chicago, IL (US);
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01); A61K 31/4439 (2006.01); C07D 209/10 (2006.01); C07D 209/08 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); C07D 209/08 (2013.01); C07D 209/10 (2013.01); C07D 401/12 (2013.01);
Abstract
Indoline sulfonamide compounds that can inhibit DapE and/or bacterial metallo-β-lactamases (MBLs), such as NDM-1, are disclosed. Also disclosed are methods of treating an individual suffering from a bacterial infection using the indoline sulfonamide compounds disclosed herein.