The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 2021

Filed:

Sep. 20, 2019
Applicant:

Kempharm, Inc., Celebration, FL (US);

Inventors:

Travis Mickle, Kissimmee, FL (US);

Sven Guenther, Coralville, IA (US);

Guochen Chi, Coralville, IA (US);

Assignee:

KemPharm, Inc., Celebration, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/4545 (2006.01); A61K 47/54 (2017.01); C07D 401/12 (2006.01); C07D 211/34 (2006.01); A61K 31/4458 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 9/0053 (2013.01); A61K 31/4458 (2013.01); A61K 31/4545 (2013.01); A61K 47/545 (2017.08); C07D 211/34 (2013.01);
Abstract

The present technology is directed to d-threo-methylphenidate conjugates and a composition comprising d-threomethylphenidate conjugated to nicotinoyl-L-serine, or salt thereof. The present technology also relates to a composition comprising at least one conjugate of d-methylphenidate having at least two or more chiral centers. The composition is optically active. The present technology additionally relates to oral formulations and pharmaceutical kits comprising at least one d-threo-methylphenidate conjugate. The pharmaceutical kit may comprise a specified amount of individual doses in a package. Each individual dose in the package may contain a pharmaceutically effective amount of a conjugate of d-threo methylphenidate.


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