The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 2021
Filed:
Apr. 30, 2019
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventor:
Alexander Flohr, Lörrach, DE;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 243/24 (2006.01); C07D 243/22 (2006.01); C07D 401/04 (2006.01); A61P 25/28 (2006.01); A61P 25/18 (2006.01);
U.S. Cl.
CPC ...
C07D 243/24 (2013.01); C07D 243/22 (2013.01); C07D 401/04 (2013.01); A61P 25/18 (2018.01); A61P 25/28 (2018.01);
Abstract
The present invention provides compounds that are muscarinic M1 receptor positive allosteric modulators (PAM) and useful in the treatment of diseases, mediated by the muscarinic M1 receptor, such as Alzheimer's disease, cognitive impairment, schizophrenia, pain or sleep disorders, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances.