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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11021444 B1

PDFFull Text
Date of Patent:
Jun. 01, 2021

Filed:

Oct. 19, 2018

Antiviral compounds

Applicant:

Janssen Biopharma, Inc., South San Francisco, CA (US);

Inventors:

Guangyi Wang, Carlsbad, CA (US);

Leonid Beigelman, San Mateo, CA (US);

Anh Truong, Burlingame, CA (US);

Carmela Napolitano, Verona, IT;

Daniele Andreotti, Verona, IT;

Haiying He, Shanghai, CN;

Karin Ann Stein, Moutain View, CA (US);

Assignee:

Janssen BioPharma, Inc., South San Francisco, CA (US);

Attorney:

Morrison & Foerster LLP

Primary Examiner:

Po-Chih Chen

Int. Cl.
CPC ...
C07D 213/40 (2006.01); A61K 45/06 (2006.01); A61K 31/4355 (2006.01); A61K 31/505 (2006.01); A61K 31/427 (2006.01); A61K 31/4196 (2006.01); A61K 31/422 (2006.01); A61K 31/4365 (2006.01); A61K 31/4439 (2006.01); A61K 31/4178 (2006.01); A61K 31/4418 (2006.01); A61K 31/4436 (2006.01); C07D 491/052 (2006.01); C07D 207/273 (2006.01); C07D 417/12 (2006.01); C07D 405/12 (2006.01); C07D 401/06 (2006.01); C07D 413/06 (2006.01); C07D 413/12 (2006.01); C07D 417/06 (2006.01); C07D 409/14 (2006.01); C07D 233/64 (2006.01); C07D 491/048 (2006.01); C07D 401/12 (2006.01); C07D 213/65 (2006.01); C07D 471/04 (2006.01); C07D 239/34 (2006.01); C07D 417/04 (2006.01); C07D 413/04 (2006.01); C07D 401/04 (2006.01); C07D 495/14 (2006.01); C07D 409/04 (2006.01); A61K 31/437 (2006.01); A61K 31/444 (2006.01); A61K 31/4709 (2006.01);
U.S. Cl.
CPC ...
C07D 213/40 (2013.01); A61K 31/4178 (2013.01); A61K 31/4196 (2013.01); A61K 31/422 (2013.01); A61K 31/427 (2013.01); A61K 31/437 (2013.01); A61K 31/4355 (2013.01); A61K 31/4365 (2013.01); A61K 31/444 (2013.01); A61K 31/4418 (2013.01); A61K 31/4436 (2013.01); A61K 31/4439 (2013.01); A61K 31/4709 (2013.01); A61K 31/505 (2013.01); A61K 45/06 (2013.01); C07D 207/273 (2013.01); C07D 213/65 (2013.01); C07D 233/64 (2013.01); C07D 239/34 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01); C07D 413/04 (2013.01); C07D 413/06 (2013.01); C07D 413/12 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 491/052 (2013.01); C07D 495/14 (2013.01); A61K 2300/00 (2013.01); C12N 2760/18511 (2013.01);
Abstract

Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).

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