The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 2021

Filed:

Dec. 10, 2018
Applicant:

Sensor Kinesis Corporation, Los Angeles, CA (US);

Inventors:

Yehoshua Shachar, Santa Monica, CA (US);

Roger Kornberg, Atherton, CA (US);

Assignee:

Autonomous Medical Devices Inc., Santa Monica, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 33/543 (2006.01); G01N 29/02 (2006.01); G01N 29/22 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); G01N 29/022 (2013.01); G01N 29/222 (2013.01); G01N 33/54373 (2013.01); B01L 2200/027 (2013.01); B01L 2200/04 (2013.01); B01L 2200/18 (2013.01); B01L 2300/025 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0887 (2013.01); B01L 2400/0436 (2013.01); B01L 2400/0475 (2013.01); B01L 2400/0605 (2013.01); G01N 2291/022 (2013.01); G01N 2291/0255 (2013.01); G01N 2291/0256 (2013.01);
Abstract

A system and method for performing a portable, fast, field assay of a small sample biological analyte includes a microfluidic cartridge and a reader with which the microfluidic cartridge is selectively communicated. A closed microfluidic circuit mixes and recirculates the analyte with a buffer. A shear horizontal surface acoustic wave (SAW) detector communicates with the microfluidic circuit and has a plurality of channels including at least one functionalized sensing channel in which the mixed analyte and buffer is recirculated and sensed. Capture of the analyte is amplified by recirculation of the analyte and buffer, and detection is amplified by use of an all-purpose endospore display mass amplification.


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