The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 2021

Filed:

Jul. 25, 2019
Applicant:

Deutsches Krebsforschungszentrum, Heidelberg, DE;

Inventors:

Matthias Eder, Mannheim, DE;

Klaus Kopka, Dossenheim, DE;

Martin Schaefer, Neckarsteinach, DE;

Ulrike Bauder-Wuest, Schriesheim, DE;

Uwe Haberkorn, Schwetzingen, DE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 49/00 (2006.01); C07D 497/10 (2006.01); C07D 311/90 (2006.01); C07D 209/60 (2006.01); C07D 209/18 (2006.01); C07D 401/14 (2006.01); G01N 33/58 (2006.01); G01N 33/574 (2006.01); A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0002 (2013.01); A61K 49/0021 (2013.01); A61K 49/0032 (2013.01); A61K 49/0041 (2013.01); A61K 49/0052 (2013.01); A61K 51/0402 (2013.01); A61K 51/0406 (2013.01); A61K 51/0497 (2013.01); C07D 209/18 (2013.01); C07D 209/60 (2013.01); C07D 311/90 (2013.01); C07D 401/14 (2013.01); C07D 497/10 (2013.01); G01N 33/57492 (2013.01); G01N 33/582 (2013.01);
Abstract

The present invention relates to a compound or a pharmaceutically acceptable salt thereof having a chemical structure comprising: (A) at least one motif specifically binding to cell membranes of neoplastic cells; (B) at least one chelator moiety of radiometals; and (C) at least one dye moiety; wherein said compound has a molecular weight of not more than 5 kDa. Further, the invention refers to a method for producing such compound and to the in vivo and in vitro uses thereof.


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