The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 2021
Filed:
Apr. 12, 2016
Applicant:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Inventors:
Fei Wen, Ann Arbor, MI (US);
Eshita Khera, Ann Arbor, MI (US);
Brett Dallas Hill, Ann Arbor, MI (US);
Syed Rizvi, Ann Arbor, MI (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C12N 15/81 (2006.01); A61K 39/145 (2006.01); A61K 39/21 (2006.01); C07K 14/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/21 (2013.01); C12N 15/81 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/70 (2013.01); C07K 14/395 (2013.01); C12N 2740/16023 (2013.01); C12N 2740/16034 (2013.01); C12N 2760/14123 (2013.01); C12N 2760/14134 (2013.01); C12N 2760/16123 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16223 (2013.01); C12N 2800/102 (2013.01);
Abstract
Provided herein are membrane enveloped virus-like particles (VLPs), and methods of use and synthesis thereof. In particular, yeast-cell-derived VLPs are provided that comprise surface-displayed glycoproteins and/or multiple virally-derived proteins.