The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 2021

Filed:

Apr. 19, 2016
Applicant:

General Hospital of Chinese Pla Northern Theater Command, Shenyang, CN;

Inventors:

Yaling Han, Shenyang, CN;

Chenghui Yan, Shenyang, CN;

Dan Liu, Shenyang, CN;

Xiaoxiang Tian, Shenyang, CN;

Yang Li, Shenyang, CN;

Xiaolin Zhang, Shenyang, CN;

Haixu Song, Shenyang, CN;

Meili Liu, Shenyang, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/00 (2006.01); A61K 38/17 (2006.01); G01N 33/68 (2006.01); C07K 14/47 (2006.01); A01K 67/027 (2006.01); A61P 9/10 (2006.01); C12N 15/52 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/17 (2013.01); A01K 67/0276 (2013.01); A61P 9/10 (2018.01); C07K 14/4702 (2013.01); C12N 15/52 (2013.01); G01N 33/68 (2013.01); G01N 33/6893 (2013.01); A01K 2217/077 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0375 (2013.01); A61K 48/00 (2013.01); G01N 2800/324 (2013.01); G01N 2800/325 (2013.01);
Abstract

The present invention relates to a medical use of Cellular Repressor of E1A-stimulated Genes (CREG), in particular to a use of CREG protein or active fragment thereof in manufacture of a medicament for preventing and/or treating myocardial infarction, a use in manufacture of a medicament for preventing and/or treating ventricular remodeling after myocardial infarction and heart failure after myocardial infarction, a use in manufacture of a medicament for prevention and/or treatment of myocardial ischemia-reperfusion injury, a use in manufacture of a medicament for prevention and/or treatment of salt-sensitive hypertensive myocardial fibrosis.


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