The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 2021
Filed:
Apr. 20, 2016
Applicant:
University of Massachusetts, Boston, MA (US);
Inventors:
Miguel Sena Esteves, Westford, MA (US);
Cara Weismann, Worcester, MA (US);
Diane Golebiowski, Lexington, MA (US);
Lorelei Stoica, Worcester, MA (US);
Assignee:
University of Massachusetts, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/761 (2015.01); A61K 48/00 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C12N 15/861 (2006.01); C12N 15/86 (2006.01); C12N 9/24 (2006.01); C12N 9/38 (2006.01);
U.S. Cl.
CPC ...
A61K 35/761 (2013.01); A61K 48/00 (2013.01); A61K 48/0058 (2013.01); A61K 48/0066 (2013.01); A61P 25/28 (2018.01); A61P 43/00 (2018.01); C12N 9/2402 (2013.01); C12N 9/2471 (2013.01); C12N 15/86 (2013.01); C12N 15/861 (2013.01); C12N 2750/14143 (2013.01); C12Y 302/01023 (2013.01); C12Y 302/01052 (2013.01);
Abstract
Aspects of the invention relate to recombinant adeno-associated viruses (rAAVs). In some aspects, the rAAVs comprise artificial genetic regulatory elements that modulate transgene expression. In some aspects, the disclosure relates to the treatment of lysosomal storage disorders.