The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 2021

Filed:

Nov. 07, 2017
Applicant:

Cancer Research Technology Limited, London, GB;

Inventors:

Emma L. Carswell, Cambridge, GB;

Mark David Charles, Cambridge, GB;

Chukuemeka Tennyson Ekwuru, Cambridge, GB;

Frederic Elustondo, Bordeaux, FR;

Katherine M. Fowler, Cambridge, GB;

Gregory R. Ott, West Chester, PA (US);

Jonathan R. Roffey, Cambridge, GB;

Joanna L. Brookfield, Cambridge, GB;

Daniel James Ford, Sydney, AU;

Mathew L. Calder, Cambridge, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); A61K 31/506 (2006.01); A61K 31/437 (2006.01); A61K 31/551 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/437 (2013.01); A61K 31/551 (2013.01); C07D 403/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to compounds of formula I as defined herein, and salts and solvates thereof, that function as inhibitors of cell division cycle 7 (Cdc7) kinase enzyme activity. The present invention also relates to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which Cdc7 kinase activity is implicated.


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