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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11020360 B1

PDFFull Text
Date of Patent:
Jun. 01, 2021

Filed:

Apr. 24, 2020

Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid

Applicant:

Bellus Health, Inc., Laval, CA;

Inventors:

Xianqi Kong, Dollard-des-Ormeaux, CA;

Mohamed Atfani, Laval, CA;

Benoit Bachand, Saint-Laurent, CA;

Abderrahim Bouzide, Laval, CA;

Stephane Ciblat, Montreal, CA;

Sophie Levesque, Mirabel, CA;

David Migneault, Laval, CA;

Isabelle Valade, Laval, CA;

Xinfu Wu, Laval, CA;

Daniel Delorme, Saint-Lazare, CA;

Assignee:

Bellus Health Inc., Laval, CA;

Attorney:

Cooley LLP

Primary Examiner:

Jonathan S Lau

Int. Cl.
CPC ...
C07D 323/02 (2006.01); A61K 31/145 (2006.01); C07C 309/15 (2006.01); C07D 233/64 (2006.01); C07K 5/062 (2006.01); C07K 5/068 (2006.01); C07K 5/083 (2006.01); C07C 309/18 (2006.01); C07C 309/19 (2006.01); C07C 309/24 (2006.01); C07H 7/02 (2006.01); C07H 15/12 (2006.01); C07J 9/00 (2006.01); C12P 13/00 (2006.01); C07D 317/40 (2006.01); C07D 207/16 (2006.01); C07D 209/20 (2006.01); C07D 217/24 (2006.01); C07D 291/02 (2006.01); C07D 333/24 (2006.01); C12P 11/00 (2006.01); A61K 47/54 (2017.01); A61K 47/64 (2017.01); C07D 285/36 (2006.01); C07D 285/38 (2006.01);
U.S. Cl.
CPC ...
A61K 31/145 (2013.01); A61K 47/54 (2017.08); A61K 47/542 (2017.08); A61K 47/545 (2017.08); A61K 47/549 (2017.08); A61K 47/554 (2017.08); A61K 47/64 (2017.08); C07C 309/15 (2013.01); C07C 309/18 (2013.01); C07C 309/19 (2013.01); C07C 309/24 (2013.01); C07D 207/16 (2013.01); C07D 209/20 (2013.01); C07D 217/24 (2013.01); C07D 233/64 (2013.01); C07D 285/36 (2013.01); C07D 285/38 (2013.01); C07D 291/02 (2013.01); C07D 317/40 (2013.01); C07D 323/02 (2013.01); C07D 333/24 (2013.01); C07H 7/02 (2013.01); C07H 15/12 (2013.01); C07J 9/005 (2013.01); C07K 5/0606 (2013.01); C07K 5/06026 (2013.01); C07K 5/06052 (2013.01); C07K 5/06069 (2013.01); C07K 5/06086 (2013.01); C07K 5/081 (2013.01); C07K 5/0806 (2013.01); C12P 11/00 (2013.01); C12P 13/001 (2013.01); Y02P 20/55 (2015.11);
Abstract

The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compound that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to the prevention and treatment of Alzheimer's disease.

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