The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2021
Filed:
Jun. 17, 2015
Immunocore Limited, Abingdon Oxfordshire, GB;
Adaptimmune Limited, Abingdon Oxfordshire, GB;
Brian John Cameron, Abingdon, GB;
Annelise Brigitte Vuidepot, Abingdon, GB;
Bent Karsten Jakobsen, Abingdon, GB;
Immunocore Limited, Abingdon Oxfordshire, GB;
Adaptimmune Limited, Abingdon Oxfordshire, GB;
Abstract
The invention provides a method for predicting whether a binding peptide, which binds to a target peptide presented by a Major Histocompatibility Complex (MHC) and is for administration to a subject, has the potential to cross react with another peptide in the subject in vivo. The method comprises the steps of identifying at least one binding motif in the target peptide to which the binding peptide binds; and searching for peptides that are present in the subject that comprise the at least one binding motif and that are not the target peptide. The presence of one or more such peptides indicates that the binding peptide has the potential to cross react in vivo.