The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2021

Filed:

Apr. 14, 2017
Applicant:

Board of Trustees of the University of Arkansas, Little Rock, AR (US);

Inventors:

Alexandru S. Biris, Little Rock, AR (US);

Zeid A. Nima, Little Rock, AR (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/553 (2006.01); G01N 33/574 (2006.01); A61K 31/704 (2006.01); A61K 49/00 (2006.01); A61K 47/68 (2017.01); H01F 1/00 (2006.01); A61K 47/69 (2017.01); A61K 9/00 (2006.01); B82Y 15/00 (2011.01); B82Y 30/00 (2011.01); B82Y 5/00 (2011.01); G01N 33/531 (2006.01); A61K 31/337 (2006.01); A61K 41/00 (2020.01); B01J 13/22 (2006.01); B32B 15/02 (2006.01); B01J 13/06 (2006.01); B01J 13/20 (2006.01); B01J 13/02 (2006.01); B82Y 40/00 (2011.01); A61N 1/40 (2006.01);
U.S. Cl.
CPC ...
G01N 33/553 (2013.01); A61K 31/337 (2013.01); A61K 31/704 (2013.01); A61K 41/0052 (2013.01); A61K 47/6849 (2017.08); A61K 47/6923 (2017.08); A61K 49/0065 (2013.01); B01J 13/02 (2013.01); B01J 13/06 (2013.01); B01J 13/20 (2013.01); B01J 13/22 (2013.01); B32B 15/02 (2013.01); G01N 33/531 (2013.01); G01N 33/57492 (2013.01); H01F 1/0054 (2013.01); A61K 9/0092 (2013.01); A61N 1/406 (2013.01); B82Y 5/00 (2013.01); B82Y 15/00 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01);
Abstract

A nanocomposite for detection and treatment of a target of interest including tumor cells or pathogens includes at least one nanostructure, each nanostructure having a core and a shell surrounding the core; a reporter assembled on the shell of each nanostructure; and a layer of a treating agent and a targeting agent conjugated to the reporter. In use, the nanocomposite targets to the target of interest according to the targeting agent and releases the treating agent and the nanostructure therein for therapeutic treatment of the target of interest, and the target of interest transmits at least one signature responsive to the reporter for detection of the target of interest.


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