The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2021

Filed:

Nov. 02, 2016
Applicant:

Swansea University, Swansea, GB;

Inventor:

Paul Dyson, Swansea, GB;

Assignee:

Swansea University, Swansea, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/88 (2006.01); A61P 35/00 (2006.01); A61K 35/74 (2015.01); A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 35/74 (2013.01); A61P 35/00 (2018.01); C12N 15/1136 (2013.01); C12N 15/1137 (2013.01); C12N 15/88 (2013.01); A61K 2035/11 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); C12N 2330/51 (2013.01);
Abstract

The invention relates to a genetically transformed or transfected bacterial cell chromosome wherein said cell is made to express interfering RNA (siRNA) active against at least one gene encoding a cancer promoting or sustaining protein such as an oncogene, a chemo-resistant gene or a metabolic gene; siRNA cassette encoding at least one siRNA active against said gene; a bacterial cell with said siRNA cassette integrated within the bacterial chromosome; a method of treating cancer, particularly but not exclusively prostate, breast or colorectal cancer, employing the use of said bacterial cell with a chromosomally integrated siRNA cassette; and use of said bacterial cell with a chromosomally integrated siRNA cassette to treat said cancer.


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Dyson, Paul. (2021). Cancer therapy (U.S. Patent No. 11015199). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11015199

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