The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2021
Filed:
Nov. 06, 2015
Applicant:
Kineta Chronic Pain, Llc, Seattle, WA (US);
Inventor:
Jeffrey Jerard Posakony, Seattle, WA (US);
Assignee:
Kineta Chronic Pain, LLC, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); A61P 29/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/43504 (2013.01); A61K 47/542 (2017.08); A61K 47/60 (2017.08); A61P 29/00 (2018.01); C07K 14/43509 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/60 (2013.01);
Abstract
The present disclosure describes analog conotoxin peptides of the α-conotoxin peptide RgIA. These analog conotoxin peptides block the α9α10 subtype of the nicotinic acetylcholine receptor (nAChR) and can be used for treating pain and inflammation including inflammatory pain, cancer related pain, and neuropathic pain. The RgIA analogs described in the present invention include a variety of sequence modifications and chemical modifications that are introduced to improve the drug-like characteristics of RgIA analogs and thereby increase their therapeutic value.