The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2021

Filed:

Mar. 19, 2018
Applicants:

The Royal Institution for the Advancement of Learning/mcgill University, Montreal, CA;

Hong Kong Polytechnic University, Kowloon, HK;

Inventors:

Masad J. Damha, St-Hubert, CA;

Matthew Hassler, Saskatoon, CA;

Tak-Hang Chan, Toronto, CA;

Mallikarjuna Reddy Nandyala, Montreal, CA;

Robert Alexander Donga, Saint-Bruno, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/60 (2006.01); C07F 9/54 (2006.01); C07F 9/655 (2006.01); C07F 9/6558 (2006.01); C07H 19/02 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); C40B 50/16 (2006.01); C40B 80/00 (2006.01);
U.S. Cl.
CPC ...
C07F 9/54 (2013.01); C07D 233/60 (2013.01); C07F 9/5407 (2013.01); C07F 9/5442 (2013.01); C07F 9/5456 (2013.01); C07F 9/65515 (2013.01); C07F 9/65586 (2013.01); C07H 19/02 (2013.01); C07H 21/00 (2013.01); C07H 21/02 (2013.01); C40B 50/16 (2013.01); C40B 80/00 (2013.01);
Abstract

The invention relates to the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. In another aspect, the invention relates to compounds of formula (II): processes for making these compounds, and the use thereof in the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. The invention also relates to methods of synthesis of oligomers, including but not limited to oligopeptides, oligosaccharides and oligonucleotides, particularly oligoribonucleotides and also oligodeoxyribonucleotides, in solution systems, and ionic tag linkers for use in methods provided herein.


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