The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2021
Filed:
Jul. 22, 2020
Sun Pharma Advanced Research Company Limited, Maharashtra, IN;
Rajan Kumar Pal, Vadodara, IN;
Biswajit Samanta, Vadodara, IN;
Jayraj Dilipbhai Aradhye, Vadodara, IN;
Sandeep Pankajkumar Pathak, Vadodara, IN;
Kaushik Dhanjibhai Prajapati, Vadodara, IN;
Bhavesh Mohanbhai Panchal, V.V. Nagar, IN;
Trinadha Rao Chitturi, Vadodara, IN;
SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED, Maharashtra, IN;
Abstract
A selective estrogen receptor degrader (SERD), a compound 3-(3,5-difluorophenyl)-2-[4-[(E)-3-[3-(fluoromethyl)azetidin-1-yl]prop-1-enyl]phenyl]-4-methyl-2H-chromen-7-ol, and its S enantiomer, (2S)-3-(3,5-difluorophenyl)-2-[4-[(E)-3-[3-(fluoromethyl)azetidin-1-yl]prop-1-enyl]phenyl]-4-methyl-2H-chromen-7-ol, or pharmaceutically acceptable salts thereof. Also provided are processes for their preparation. Also provided for is the use of these compounds for the treatment of diseases which are related to modulation of estrogen receptors, such as ER-positive breast cancer.