The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2021
Filed:
Nov. 26, 2019
Pfizer Inc., New York, NY (US);
Ariamala Gopalsamy, Lexington, MA (US);
Arjun Venkat Narayanan, Cambridge, MA (US);
Agustin Casimiro-Garcia, Concord, MA (US);
Chulho Choi, Mystic, CT (US);
David Hepworth, Concord, MA (US);
David Walter Piotrowski, Waterford, CT (US);
Hatice Gizem Yayla, Mystic, CT (US);
Jayasankar Jasti, East Lyme, CT (US);
Lee Richard Roberts, Belmont, MA (US);
Lyn Howard Jones, Winchester, MA (US);
Mihir Dineshkumar Parikh, East Greenwich, RI (US);
Ming Zhu Chen, Mystic, CT (US);
Olugbeminiyi Omezia Fadeyi, Harvard, MA (US);
Ralph Pelton Robinson, Jr., Gales Ferry, CT (US);
Robert Lee Dow, Quincy, MA (US);
Shawn Cabral, Groton, CT (US);
Pfizer Inc., New York, NY (US);
Abstract
The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to HbS modulators of formula (I) or tautomers thereof, or pharmaceutically acceptable salts of said modulators or tautomers thereof, wherein X, Y, Rand Rare as defined in the description. HbS modulators are potentially useful in the treatment of a wide range of disorders, including sickle cell disease (SCD).