The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2021
Filed:
Jan. 05, 2017
Universite Paris-sud, Orsay, FR;
Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;
Mouâd Alami, Bussy Saint Georges, FR;
Abdallah Hamze, Massy, FR;
Jean-Daniel Brion, Saint Leu la Foret, FR;
Jérôme Bignon, Le Val Saint Germain, FR;
Joëlle Dubois, Gometz-la-Ville, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), Paris, FR;
UNIVERSITE PARIS-SUD, Orsay, FR;
Abstract
The present invention relates to the design of novel molecules, referred to as 'multi-target' molecules, having a double pharmacophore and acting both as inhibitors of histone deacetylases (HDACs) and as inhibitors of tubulin polymerisation. The invention also describes the method for synthesising the 'multi-target' molecules and their use in the treatment of cancer, a pharmaceutical composition comprising at least one “multi-target” molecule, and the use of such compositions in the treatment of cancer.